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Special Issue Information Dear Colleagues, The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues. Transferring γ-phosphate onto diverse substrates enables kinases to regulate key cellular functions. As many human diseases result from the mutation and overexpression of kinases, targeting of this enzyme class symbolizes an important strategy for drug development. Many of these kinases are associated with human cancer initiation and progression. The recent development of small-molecule kinase inhibitors for the treatment of [...]

DISCOVERY LAB: RICERCA PER PASSIONE - VIII EDIZIONE European Biotech Week, 27 novembre – 3 ottobre 2021 Promossa dall’Associazione Nazionale per lo Sviluppo delle Biotecnologie Assobiotec, dal 27 settembre al 3 ottobre 2021 si terrà la European BiotechWeek (EBW). Una settimana dedicata alle biotecnologie nei suoi diversi settori di applicazione: dalla terapia alla diagnostica, dall’agroalimentare ai processi industriali, passando per il risanamento ambientale fino alle energie rinnovabili. Un programma ricco di eventi, dibattiti, mostre. Il 27 e 28 settembre 2021 l’Istituto per l’Endocrinologia ed [...]

CELLULE STAMINALI: DOTTOR JEKYLL E MISTER HYDE NOTTE EUROPEA DEI RICERCATORI “MEET ME TONIGHT”: faccia a faccia con CREO-CNR, la rete outreach degli Istituti CNR della Campania Il 24 settembre 2021 torna l’appuntamento con la European Researchers' Night (ERN), promosso dalla Commissione Europea. Nel progetto “Meet Me Tonight”, coordinato dall’Università FEDERICO II di Napoli, in Campania sono coinvolti oltre 50 soggetti pubblici e privati come Atenei, Enti di ricerca, Musei, impegnati nella divulgazione della scienza per una giornata “Faccia a faccia” con la ricerca. L’Istituto per l’Endocrinologia [...]

Special Issue "Targeted Cancer Therapy and Mechanisms of Resistance 2.0" A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics". Deadline for manuscript submissions: 30 September 2021. Share This Special Issue Special Issue Editor Prof. Dr. Valentina De Falco Guest Editor Institute Experimental Endocrinology and Oncology "Gaetano Salvatore" IEOS, Università degli Studi di Napoli Federico II, Naples, Italy Interests: cancer; kinase inhibitor; target therapy; signal transduction; [...]

Epigenetic Mechanisms of Environmental Diseases Message from the Guest Editors This Special Issue, “Epigenetic Mechanisms of Environmental Diseases” will mainly focus on environmental influences on human health. The human genome encodes approximately 30,000 genes. It is estimated that over 8,000 human diseases are caused by defects in single genes. These unifactorial or monogenic diseases are individually rare and affect approximately one percent of the human population. In contrast, complex human diseases such as cancer and type 2 diabetes are believed to involve both susceptibility genes and their [...]