The Center for Experimental Endocrinology and Oncology, part of the National Research Council, was established in 1969; in 2001, following legal reforms, it became an Institute maintaining, as a mark of continuity with the past, the same description, Institute for Experimental Endocrinology and Oncology (in Italian "Istituto per l’Endocrinologia e Oncologia Sperimentale"- IEOS). Both in the past as a Center and in the present as an Institute, it is a scientific environment focused on basic and applied research in the fields of endocrinology, oncology, and immunology. From its very beginning, the IEOS has been a research center characterized by a strong synergism between the National Research Council and Universities, in particular the University of Naples Federico II, which over the years has allowed an improvement in the quality of our research. With many university researchers associated to IEOS and many IEOS researchers being part of university research groups, it has been possible to achieve the critical mass needed for internationally competitive research. Through these close relationships and exchanges, the two Institutions have pursued complementary goals and objectives and it has been possible to guarantee continuity, increase scientific output, broaden the scope of collaborations and develop new research activities. The scientific results achieved over the years have been acknowledged both nationally and internationally; this is directly correlated with the interdisciplinary and multidisciplinary skills of the National Research Council and University researchers, living together in the shared research and university space. From a logistic perspective, the IEOS is in a strategic and stimulating position for biomedical research. It is located within the Medical Campus of the University of Naples Federico II; nearby are other centers of research excellence such as the CEINGE–Biotecnologie Avanzate (CEINGE–Advanced Biotechnologies), a consortium which focuses on advanced biotechnologies and their potential applications, and the National Research Council’s Institute of Biostructure and Bioimaging (IBB), which focuses on diagnostic imaging and on the development of diagnostic and therapeutic agents. Finally, not far from the IEOS is CNR-NA1, the National Research Council’s Research Area consisting of seven Institutes (IGB, IBP, ICAR, IAC, IMM, IBBR, IBAF), which is another important organization for biomedical research. All this contributes to the creation of an intellectually lively environment, offering interdisciplinary connections and complementary skillsets; early career researchers here have the opportunity to participate to seminars, research workshops, and career development workshops on topics such as project management, technology transfer, quality control, and employment pathways.
Our research Research
at the IEOS falls under three main themes:
- Cellular and molecular mechanisms regulating the proliferation, the differentiation and transformation of the cells;
- Genomics and epigenomics of diabetes and other chronic illnesses;
- Mechanisms regulating the interactions between the energetic/nutritional state and the immune system;
Strong synergies and cooperation among the different themes create opportunities for transdisciplinary research in the biomedical domain. The IEOS receives funding for competitive research from the European Union, the Ministry for Education, University and Research, the Italian Association for Cancer Research, Telethon, and other national and international funding bodies.