Publications

Year 2011

  Balato N, Nino M, Patruno C, Matarese G, Ayala F. "Eczemas" and leptin. Esposito CL, Passaro D, Longobardo I, Condorelli G, Marotta P, Affuso A, de Franciscis V, Cerchia L. A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death. Sepe M, Festa L, Tolino F, Bellucci L, Sisto L, Alfano D, Ragno P, Calabrò V, de Franciscis V, La Mantia G, Pollice A. A regulatory mechanism involving TBP-1/Tat-Binding Protein 1 and Akt/PKB in the control of cell proliferation. Leone V, D'Angelo D, Ferraro A, Pallante P, Rubio I, Santoro M, Croce CM, Fusco A. A TSH-CREB1-microRNA Loop Is Required for Thyroid Cell Growth. Di Domenico M, Ricciardi C, Fusco A, Pierantoni GM. Anti-VEGF therapy in breast and lung mouse models of cancers. Angrisano T, Sacchetti S, Natale F, Cerrato A, Pero R, Keller S, Peluso S, Perillo B, Avvedimento VE, Fusco A, Bruni CB, Lembo F, Santoro M, Chiariotti L. Chromatin and DNA methylation dynamics during retinoic acid-induced RET gene transcriptional activation in neuroblastoma cells. Cocozza S, Akhtar MM, Miele G, MONTICELLI A. CpG islands undermethylation in human genomic regions under selective pressure. Andreucci M, Lucisano G, Faga T, Bertucci B, Tamburrini O, Pisani A, Sabbatini M, Salzano S, Vitale M, Fuiano G, Michael A. Differential activation of signaling pathways involved in cell death, survival and inflammation by radiocontrast media in human renal proximal tubular cells. Esposito F, Boscia F, Franco R, Tornincasa M, Fusco A, Kitazawa S, Looijenga LH, Chieffi P. Down-regulation of oestrogen receptor-² associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas. Bertoni A, Giuliano P, Galgani M, Rotoli D, Ulianich L, Adornetto A, Santillo MR, Porcellini A, Avvedimento VE. Early and late events induced by polyq-expanded proteins: identification of a common pathogenic property of polyq-expanded proteins. Moon HS, Matarese G, Brennan AM, Chamberland JP, Liu X, Fiorenza CG, Mylvaganam GH, Abanni L, Carbone F, Williams CJ, De Paoli AM, Schneider BE, Mantzoros CS. Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance. Borbone E, Troncone G, Ferraro A, Jasencakova Z, Stojic L, Esposito F, Hornig N, Fusco A, Orlando V. Enhancer of zeste homolog 2 overexpression has a role in the development of anaplastic thyroid carcinomas. Di Paola R, Caporarello N, Marucci A, Dimatteo C, Iadicicco C, Del Guerra S, Prudente S, Sudano D, Miele C, Parrino C, Piro S, Beguinot F, Marchetti P, Trischitta V, Frittitta L. Source ENPP1 affects insulin action and secretion: evidences from in vitro studies. Ulianich L, Terrazzano G, Annunziatella M, Ruggiero G, Beguinot F, Di Jeso B. ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity. Fedele M, Visone R, De Martino I, Palmieri D, Valentino T, Esposito F, Klein-Szanto A, Arra C, Ciarmiello A, Croce CM, Fusco A. Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice. Chiefari E, Tanyolaç S, Paonessa F, Pullinger CR, Capula C, Iiritano S, Mazza T, Forlin M, Fusco A, Durlach V, Durlach A, Malloy MJ, Kane JP, Heiner SW, Filocamo M, Foti DP, Goldfine ID, Brunetti A. Functional variants of the HMGA1 gene and type 2 diabetes mellitus. Pisanti S, Picardi P, Prota L, Proto MC, Laezza C, McGuire PG, Morbidelli L, Gazzerro P, Ziche M, Das A, Bifulco M. Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis. Proietti A, Ugolini C, Melillo RM, Crisman G, Elisei R, Santoro M, Minuto M, Vitti P, Miccoli P, Basolo F. Higher intratumoral expression of CD1a, tryptase, and CD68 in a follicular variant of papillary thyroid carcinoma compared to adenomas: correlation with clinical and pathological parameters. Lapilla M, Gallo B, Martinello M, Procaccini C, Costanza M, Musio S, Rossi B, Angiari S, Farina C, Steinman L, Matarese G, Constantin G, Pedotti R. Histamine regulates autoreactive T cell activation and adhesiveness in inflamed brain microcirculation. Palmieri D, Valentino T, D'Angelo D, De Martino I, Postiglione I, Pacelli R, Croce CM, Fedele M, Fusco A. HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents. Pierantoni GM, Esposito F, Tornincasa M, Rinaldo C, Viglietto G, Soddu S, Fusco A. Homeodomain-interacting protein kinase-2 stabilizes p27(kip1) by its phosphorylation at serine 10 and contributes to cell motility. Di Palma T, Conti A, de Cristofaro T, Scala S, Nitsch L, Zannini M. Identification of Novel Pax8 Targets in FRTL-5 Thyroid Cells by Gene Silencing and Expression Microarray Analysis. Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Calì G, Amendola E, Sanges R, Zannini M, Scarfò M, De Luca P, Nitsch L, Di Lauro R, De Felice M. In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1. Andreozzi F, Procopio C, Greco A, Mannino GC, Miele C, Raciti GA, Iadicicco C, Beguinot F, Pontiroli AE, Hribal ML, Folli F, Sesti G. Increased levels of theAkt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance. Shetty GK, Matarese G, Magkos F, Moon HS, Liu X, Brennan AM, Mylvaganam G, Sykoutri D, Depaoli AM, Mantzoros CS. Leptin administration to overweight and obese subjects for 6 months increases free leptin concentrations but does not alter circulating hormones of the thyroid and IGF axes during weight loss induced by a mild hypocaloric diet. Procaccini C, Jirillo E, Matarese G. Leptin as an immunomodulator. Chou SH, Chamberland JP, Liu X, Matarese G, Gao C, Stefanakis R, Brinkoetter MT, Gong H, Arampatzi K, Mantzoros CS. Leptin is an effective treatment for hypothalamic amenorrhea. Raciti GA, Iadicicco C, Ulianich L, Vind BF, Gaster M, Andreozzi F, Longo M, Teperino R, Ungaro P, Di Jeso B, Formisano P, Beguinot F, Miele C. Lo stress del reticolo endoplasmatico (RE) indotto da glucosammina inibisce l'espressione del GLUT4 nelle cellule muscolari scheletriche mediante il fattore di attivazione della trascrizione (ATF) 6. Leone V, D'Angelo D, Rubio I, de Freitas PM, Federico A, Colamaio M, Pallante P, Medeiros-Neto G, Fusco A. MiR-1 Is a Tumor Suppressor in Thyroid Carcinogenesis Targeting CCND2, CXCR4, and SDF-1{alpha}. Colamaio M, Borbone E, Russo L, Bianco M, Federico A, Califano D, Chiappetta G, Pallante P, Troncone G, Battista S, Fusco A. miR-191 Down-Regulation Plays a Role in Thyroid Follicular Tumors through CDK6 Targeting. Esposito, Carla Lucia; Catuogno, Silvia; De Franciscis, Vittorio; Cerchia, Laura New insight into clinical development of nucleic acid aptamers. Crescenzi E, Pacifico F, Lavorgna A, De Palma R, D'Aiuto E, Palumbo G, Formisano S, Leonardi A. NF-jB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells. Cerchia L, de Franciscis V. Nucleic acid aptamers against protein kinases. Procaccini C, Carbone F, Galgani M, La Rocca C, De Rosa V, Cassano S, Matarese G. Obesity and susceptibility to autoimmune diseases. Oriente F, Iovino S, Cabaro S, Cassese A, Longobardi E, Miele C, Ungaro P, Formisano P, Blasi F, Beguinot F. Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase. Malfitano AM, Sosa S, Laezza C, De Bortoli M, Tubaro A, Bifulco M. Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice. Ramaglia L, Postiglione L, Di Spigna G, Capece G, Salzano S, Rossi G. Sandblasted-acid-etched titanium surface influences in vitro the biological behavior of SaOS-2 human osteoblast-like cells. Savastano S; Valentino R; Di Somma C; Orio F; Pivonello C; Passeretti F; Brancato V; Formisano P; Colao A; Beguinot F; Tarantino G Serum 25-Hydroxyvitamin D Levels, Phosphoprotein Enriched in Diabetes Gene Product (PED/PEA-15) and Leptin-to-Adiponectin Ratio in Women with PCOS. Amato R, Miele G, MONTICELLI A, Cocozza S. Signs of selective pressure on genetic variants affecting human height. Laatikainen, LE [ 1 ] ; Incoronato, M [ 2 ] ; Castellone, MD [ 3 ] ; Laurila, JP [ 1 ] ; Santoro, M [ 3 ] ; Laukkanen, MO [ 1,2] SOD3 Decreases Ischemic Injury Derived Apoptosis through Phosphorylation of Erk1/2, Akt, and FoxO3a. de Cristofaro T, Di Palma T, Ferraro A, Corrado A, Lucci V, Franco R, Fusco A, Zannini M. TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma. Montuori N, Bifulco K, Carriero MV, La Penna C, Visconte V, Alfano D, Pesapane A, Rossi FW, Salzano S, Rossi G, Ragno P. The cross-talk between the urokinase receptor and fMLP receptors regulates the activity of the CXCR4 chemokine receptor. Frezzetti D, Reale C, Calì G, Nitsch L, Fagman H, Nilsson O, Scarfò M, De Vita G, Di Lauro R. The microRNA-Processing Enzyme Dicer Is Essential for Thyroid Function. Formisano L, Guida N, Cocco S, Secondo A, Sirabella R, Ulianich L, Paturzo F, Di Renzo G, Canzoniero LM. The repressor element 1-silencing transcription factor is a novel molecular target for the neurotoxic effect of the polychlorinated biphenyl mixture aroclor 1254 in neuroblastoma SH-SY5Y cells. Furia A, Moscato M, Calì G, Pizzo E, Confalone E, Amoroso MR, Esposito F, Nitsch L, D'Alessio G. The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei. Di Paola R, Caporarello N, Marucci A, Dimatteo C, Iadicicco C, Del Guerra S, Prudente S, Sudano D, Miele C, Parrino C, Piro S, Beguinot F, Marchetti P, Trischitta V, Frittitta L. Trischitta V, Frittitta L. ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies. Salerno P, Garcia-Rostan G, Piccinin S, Bencivenga TC, Di Maro G, Doglioni C, Basolo F, Maestro R, Fusco A, Santoro M, Salvatore G. TWIST1 plays a pleiotropic role in determining the anaplastic thyroid cancer phenotype. De Vitis S, Sonia Treglia A, Ulianich L, Turco S, Terrazzano G, Lombardi A, Miele C, Garbi C, Beguinot F, Di Jeso B. Source Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, which, paradoxically, are apoptosis-protected in a MEK-dependent manner. Malfitano AM, Ciaglia E, Gangemi G, Gazzerro P, Laezza C, Bifulco M. Update on the endocannabinoid system as an anticancer target. Frezzetti D, De Menna M, Zoppoli P, Guerra C, Ferraro A, Bello AM, De Luca P, Calabrese C, Fusco A, Ceccarelli M, Zollo M, Barbacid M, Di Lauro R, De Vita G. Upregulation of miR-21 by Ras in vivo and its role in tumor growth.