Publications

Year 2009

  Aquila S, Guido C, Laezza C, Santoro A, Pezzi V, Panza S, Andò S, Bifulco M. A new role of anandamide in human sperm: focus on metabolism. Kisslinger A; Cantile M;Sparaneo G; Vitale N; Fabbrocini G;Chieffi P; Cillo C; Mancini FP; Tramontano D; cAMP and Pyk2 interact to regulate prostate cell proliferation and function. Bifulco M, Santoro A, Laezza C, Malfitano AM. Cannabinoid receptor CB1 antagonists state of the art and challenges. Cerchia L, Giangrande PH, McNamara JO, de Franciscis V. Cell-specific aptamers for targeted therapies. Trapasso F, Aqeilan RI, Iuliano R, Visone R, Gaudio E, Ciuffini L, Alder H, Paduano F, Pierantoni GM, Soddu S, Croce CM, Fusco A. Chiefari E, Paonessa F, Iiritano S, Le Pera I, Palmieri D, Brunetti G, Lupo A, Colantuoni V, Foti D, Gulletta E, De Sarro G, Fusco A, Brunetti A. Federico A; Pallante P; Bianco M; Ferraro A; Esposito F; Monti M; Cozzolino M; Keller S; Fedele M; Leone V; Troncone G; Chiariotti L; Pucci P; Fusco A. Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein. Laura Cerchia 1; Carla Lucia Esposito 2; Andreas H. Jacobs 3,4; Bertrand Tavitian 5; Vittorio De Franciscis 1 Differential SELEX in human glioma cell lines. Laurila JP, Castellone MD, Curcio A, Laatikainen LE, Haaparanta-Solin M, Gronroos TJ, Marjamaki P, Martikainen S, Santoro M, Laukkanen MO. Extracellular superoxide dismutase is a growth regulatory mediator of tissue injury recovery. Boscia F; Esposito CL; Di Crisci A; de Franciscis V; Annunziato L; Cerchia L GDNF selectively induces microglial activation and neuronal survival in CA1/CA3 hippocampal regions exposed to NMDA insult through Ret/ERK signalling. Marasco D; Stilo R; Sandomenico A; Monti SM; Tizzano B; de Capua A; Varricchio E; Liguoro D; Zotti T; Formisano S; Ruvo M; Vito P Generation and functional characterization of a BCL10-inhibitory peptide that represses NF-kappaB activation Amato R, Pinelli M, Monticelli A, Marino D, Miele G, Cocozza S. Genome-wide scan for signatures of human population differentiation and their relationship with natural selection, functional pathways and diseases. Martinez Hoyos J, Ferraro A, Sacchetti S, Keller S, De Martino I, Borbone E, Pallante P, Fedele M, Montanaro D, Esposito F, Cserjesi P, Chiariotti L, Troncone G, Fusco A. HAND1 gene expression is negatively regulated by the High Mobility Group A1 proteins and is drastically reduced in human thyroid carcinomas. Borbone E, Berlingieri MT, De Bellis F, Nebbioso A, Chiappetta G, Mai A, Altucci L, Fusco A. Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation. De Martino I; Visone R; Wierinckx A; Palmieri D; Ferraro A; Cappabianca P; Chiappetta G; Forzati F; Lombardi G; Colao A; Trouillas J; Fedele M; Fusco A. HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas. Chiappetta G, Ottaiano A, Vuttariello E, Monaco M, Galdiero F, Gallipoli A, Pilotti S, Jodice G, Siranoush M, Colombo M, Ripamonti CB, Pallante PL, Radice P, Fusco A. HMGA1 protein expression in familial breast carcinoma patients. Aquila S, Guido C, Santoro A, Perrotta I, Laezza C, Bifulco M, Sebastiano A. Human Sperm Anatomy: Ultrastructural Localization of the Cannabinoid1 Receptor and a Potential Role of Anandamide in Sperm Survival and Acrosome Reaction. Nappi TC; Salerno P; Zitzelsberger H; Carlomagno F; Salvatore G; Santoro M. Identification of Polo-like kinase 1 as a potential therapeutic target in anaplastic thyroid carcinoma. Carlomagno F, Guida T, Anaganti S, Provitera L, Kjaer S, McDonald NQ, Ryan AJ, Santoro M. Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474. Bleeker FE; Lamba S; Leenstra S; Troost D; Hulsebos T; Vandertop WP; Frattini M; Molinari F; Knowles M; Cerrato A; Rodolfo M; Scarpa A; Felicioni L; Buttitta F; Malatesta S; Marchetti A; Bardelli A. IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors. Fedele M, Palmieri D, Chiappetta G, Pasquinelli R, De Martino I, Arra C, Palma G, Valentino T, Pierantoni GM, Viglietto G, Rothstein JL, Santoro M, Fusco A. Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice. Russo I, Cosentino C, Del Giudice E, Broccoletti T, Amorosi S, Cirillo E, Aloj G, Fusco A, Costanzo V, Pignata C. In ataxia-teleangiectasia betamethasone response is inversely correlated to cerebellar atrophy and directly to antioxidative capacity. Cirillo C, Sarnelli G, Esposito G, Grosso M, Petruzzelli R, Izzo P, Calì G, D'Armiento FP, Rocco A, Nardone G, Iuvone T, Steardo L, Cuomo R. Increased mucosal nitric oxide production in ulcerative colitis is mediated in part by the enteroglial-derived S100B protein. Esposito F, Pierantoni GM, Battista S, Melillo RM, Scala S, Chieffi P, Fedele M, Fusco A. Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation. Di Domenico C; Villani GR, Di Napoli D; Nusco E; Calì G; Nitsch L; Di Natale P. Intracranial gene delivery of LV-NAGLU vector corrects neuropathology in murine MPS IIIB. Cai C, Shi FD, Matarese G, La Cava A. Leptin as clinical target. Alviggi C, Clarizia R, Castaldo G, Matarese G, Colucci CC, Conforti S, Pagano T, Revelli A, De Placido G. Leptin concentrations in the peritoneal fluid of women with ovarian endometriosis are different according to the presence of a 'deep' or 'superficial' ovarian disease. Cai C, Hahn BH, Matarese G, La Cava A. Leptin in non-autoimmune inflammation. Procaccini C, LourencoEV, Matarese G, La Cava A. Leptin signaling: A key pathway in immune responses. Lourenço EV; Procaccini C; Ferrera F; Iikuni N; Singh RP; Filaci G; Matarese G; Shi FD; Brahn E; Hahn BH; La Cava A. Modulation of p38 MAPK activity in regulatory T cells after tolerance with anti-DNA Ig peptide in (NZB x NZW)F1 lupus mice. Cerrato A; De Falco V; Santoro M. Molecular genetics of medullary thyroid carcinoma: the quest for novel therapeutic targets Ferrara AM, De Sanctis L, Rossi G, Capuano S, Del Prete G, Zampella E, Gianino P, Corrias A, Fenzi G, Zannini M, Macchia PE. Mutations in TAZ/WWTR1, a co-activator of NKX2.1 and PAX8 are not a frequent cause of thyroid dysgenesis. Sarnelli G, De Giorgio R, Gentile F, Calì G, Grandone I, Rocco A, Cosenza V, Cuomo R, D'Argenio G. Myenteric neuronal loss in rats with experimental colitis: role of tissue transglutaminase-induced apoptosis. Laezza C; Caruso MG; Gentile T; Notarnicola M; Malfitano AM; Di Matola T; Messa C; Gazzerro P; Bifulco M. N6-isopentenyladenosine inhibits cell proliferation and induces apoptosis in a human colon cancer cell line DLD1. Visconti R; Grieco D New insights on oxidative stress in cancer Staibano S;Mascolo M; Mancini FP; Kisslinger A; Salvatore G; Di Benedetto M; Chieffi P;Altieri V; Prezioso D; Ilardi G;De Rosa G;Tramontano D. Overexpression of chromatin assembly factor-1 (CAF-1) p60 is predictive of adverse behaviour of prostatic cancer Oriente F; Iovino S; Cassese A; Romano C; Miele C; Troncone G; Balletta M; Perfetti A; Santulli G; Iaccarino G; Valentino R; Beguinot F; Formisano P Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-² activity and TGF-²1 expression. de Cristofaro T, Mascia A, Pappalardo A, D'Andrea B, Nitsch L, Zannini M. Pax8 protein stability is controlled by sumoylation. Viparelli F, Doti N, Monti SM, Marasco D, Dathan N, Pedone C, Miele C, Formisano P, Beguinot F, Ruvo M. Peptide antagonists of the PED-hPLD1 binding Marmolino D, Acquaviva F, Pinelli M, Monticelli A, Castaldo I, Filla A, Cocozza S. PPAR-gamma agonist Azelaoyl PAF increases frataxin protein and mRNA expression: new implications for the Friedreich's ataxia therapy. De Martino I; Visone R; Fedele M; Petrocca F; Palmieri D; Martinez Hoyos J; Forzati F; Croce CM; Fusco A. Regulation of microRNA expression by HMGA1 proteins. Santoro A, Pisanti S, Grimaldi C, Izzo AA, Borrelli F, Proto MC, Malfitano AM, Gazzerro P, Laezza C, Bifulco M. Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon Romano, S; D'Angelillo, A; Pacelli, R; Staibano, S; De Luna, E; Bisogni, R; Eskelinen, EL; Mascolo, M; Cali, G; Arra, C; Romano, MF Role of FK506-binding protein 51 in the control of apoptosis of irradiated melanoma cells Pacifico F, Leonardi A. Role of NF-kappaB in thyroid cancer. Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P. Selective disruption of insulin-like growth factor (IGF)-1 signalling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. Ruvo, M., Sandomenico, A., Marasco, D., Monti, S.M., Tizzano, B., De Capua, A., Pedone, C., Saporito, A., Vitale, R.M., Formisano, S., Stilo, R., Liguoro, D. Self-association regions in the CARD of Bcl-10 Laurila, Juha P.; Laatikainen, Lilja E.; Castellone, Maria D.; Laukkanen, Mikko O. SOD3 Reduces Inflammatory Cell Migration by Regulating Adhesion Molecule and Cytokine Expression Di Palma T.; D'Andrea B.; Liguori G.L.; Liguoro A.; de Cristofaro T.; Del Prete D.; Pappalardo A.; Mascia A.; Zannini M. TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation Castellone MD; De Falco V; Rao DM, Bellelli R; Muthu M; Basolo F; Fusco A; Gutkind JS; Santoro M. The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation. Chiefari E, Paonessa F, Iiritano S, Le Pera I, Palmieri D, Brunetti G, Lupo A, Colantuoni V, Foti D, Gulletta E, De Sarro G, Fusco A, Brunetti A. The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis. Rivas M, Mellström B, Torres B, Calì G, Ferrara AM, Terracciano D, Zannini M, Morreale de Escobar G, Naranjo JR. The DREAM protein is associated with thyroid enlargement and nodular development. Iuliano R, Raso C, Quintiero A, Pera IL, Pichiorri F, Palumbo T, Palmieri D, Pattarozzi A, Florio T, Viglietto G, Trapasso F, Croce CM, Fusco A. The eighth fibronectin type III domain of protein tyrosine phosphatase receptor J influences the formation of protein complexes and cell localization. Galgani M, Di Giacomo A, Matarese G, La Cava A. The Yin and Yang of CD4(+) regulatory T cells in autoimmunity and cancer. Cursio R, Miele C, Filippa N, Colosetti P, Auberger P, Van Obberghen E, Gugenheim J. Tyrosine phosphorylation of insulin receptor substrates during ischemia/reperfusion-induced apoptosis in rat liver. Troncone G, Guerriero E, Pallante P, Berlingieri MT, Ferraro A, Del Vecchio L, Gorrese M, Mariotti E, Iaccarino A, Palmieri EA, Zeppa P, Palombini L, Fusco A. UbcH10 expression in human lymphomas. Pisanti S, Malfitano AM, Grimaldi C, Santoro A, Gazzerro P, Laezza C, Bifulco M. Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. Sassone B, Gabrieli L, Saccà S, Boggian G, Fusco A, Pratola C, Bacchi-Reggiani ML, Padeletti L, Barold SS. Value of right ventricular-left ventricular interlead electrical delay to predict reverse remodelling in cardiac resynchronization therapy: the INTER-V pilot study. M Lodyga; V De Falco; X-h Bai; A Kapus; R M Melillo; M Santoro; M Liu XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.