Contributi in rivista

Anno 2005

Paron I, D’Ambrosio C, Scaloni A, Berlingieri MT, Pallante P, Fusco A, Bivi N, Tell G, Damante G
A differential proteomic approach to identify proteins associated with thyroid cell transformation

Fusco A, Viglietto G, Santoro M.
A new mechanism of BRAF activation in human thyroid papillary carcinomas.

Cozzolino R; Palladino P; Rossi F; Calì G; Benedetti E; Laccetti P.
Antineoplastic cyclic astin analogues kill tumour cells via caspase-mediatedinduction of apoptosis.

Cirillo P, Golino P, Calabro P, Calì G, Ragni M, De Rosa S, Cimmino G, Pacileo M, De Palma R, Forte L, Gargiulo A, Granato Corigliano F, Angri V, Spagnuolo R, Nitsch L, Chiariello M.
C-reactive protein induces tissue factor expression and promotes smooth muscle and endothelial cell proliferation.

Cantile M; Kisslinger A; Cindolo L; Schiavo G; D’anto V; Franco R; Altieri V; Gallo A; Villacci A; Tramontano D; Cillo C.
cAMP induced modifications of HOX D gene expression in prostate cells allow the identification of a chromosomal area involved in vivo with neuroendocrine differentiation of human advanced prostate cancers

Motti ML, Califano D, Troncone G, De Marco C, Migliaccio I, Palmieri E, Pezzullo L, Palombini L, Fusco A, Viglietto G.
Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localization.

Amoresano V; Incoronato M; Monti G; Pucci P; de Franciscis V; Cerchia L
Direct interactions among the tyrosine kinase receptor Ret, the GDNF and the GFR±1 molecules.

Messa C, Notarnicola M, Russo F, Cavallini A, Pallottini V, Trentalance A, Bifulco M, Laezza C, Gabriella Caruso M.
Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cells.

Acquaviva F, De Biase I, Nezi L, Ruggiero G, Tatangelo F, Pisano C, MONTICELLI A, Garbi C, Acquaviva AM, Cocozza S.
Extra-mitochondrial localisation of frataxin and its association with IscU1 during enterocyte-like differentiation of the human colon adenocarcinoma cell line Caco-2.

Cursio R, Filippa N, Miele C, Colosetti P, Auberger P, Van Obberghen E, Gugenheim J.
Fas ligand expression following normothermic liver ischemia-reperfusion.

Malfitano AM, Matarese G, Bifulco M.
From Cannabis to Endocannabinoids in Multiple Sclerosis: A Paradigm of Central Nervous System Autoimmune Diseases.

Battista S, Fedele M, Martinez Hoyos J, Pentimalli F, Pierantoni GM, Visone R, De Martino I, Croce CM, Fusco A.
High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2).

Baldassarre G, Belletti B, Battista S, Nicoloso MS, Pentimalli F, Fedele M, Croce CM, Fusco A.
HMGA1 protein expression sensitizes cells to cisplatin-induced cell death.

Chau KY, Keane-Myers AM, Fedele M, Ikeda Y, Creusot RJ, Menozzi L, Cousins DJ, Manfioletti G, Feigenbaum L, Fusco A, Ono SJ.
IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.

Matarese G, La Cava A.
Immune response in obesity models.

Zannetti A, Del Vecchio S, Romanelli A, Scala S, Saviano M, Cali’ G, Stoppelli MP, Pedone C, Salvatore M
Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells

Selleri C, Montuori N, Ricci P, Visconte V, Carriero MV, Sidenius N, Serio B, Blasi F, Rotoli B, Rossi G, Ragno P.
Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization

Foti D; Chiefari E; Fedele M; Iuliano R; Brunetti L; Paonessa F; Manfioletti G; Barbetti F; Brunetti A; Croce CM; Fusco A; Brunetti A.
Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice.

Matarese G, Moschos S, Mantzoros CS.
Leptin in immunology.

Matarese G, Carrieri PB, La Cava A, Perna F, Sanna V, De Rosa V, Aufiero D, Fontana S, Zappacosta S.
Leptin increase in multiple sclerosis associates with reduced number of CD4+CD25+ regulatory T cells.

Di Vizio D, Cito L, Boccia A, Chieffi P, Insabato L, Pettinato G, Motti ML, Schepis F, D’Amico W, Fabiani F, Tavernise B, Venuta S, Fusco A, Viglietto G.
Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.

Agarwal SK; Kennedy PA, Scacheri PC, Novotny EA, Hickman AB, Cerrato A, Rice TS, Moore JB, Rao S, Ji Y, Mateo C, Libutti SK, Oliver B, Chandrasekharappa SC, Burns AL, Collins FS, Spiegel AM, Marx SJ.
Menin molecular interactions: insights into normal functions and tumorigenesis.

Guida T, Salvatore G, Faviana P, Giannini R, Garcia-Rostan G, Provitera L, Basolo F, Fusco A, Carlomagno F, Santoro M.
Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma.

Laura Cerchia 1; Frederic Duconge 2; Carine Pestourie 2; Jocelyne Boulay 3; Youssef Aissouni 3; Karine Gombert 2; Bertrand Tavitian 2; Vittorio de Franciscis 1; Domenico Libri 3
Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase

Pannaccione A, Secondo A, Scorziello A, Calì G, Taglialatela M, Annunziato L.
Nuclear factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones.

Guarino V, Faviana P, Salvatore G, Castellone MD, Cirafici AM, De Falco V, Celetti A, Giannini R, Basolo F, Melillo RM, Santoro M.
Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness.

Celetti A, Testa D, Staibano S, Merolla F, Guarino V, Castellone MD, Iovine R, Mansueto G, Somma P, De Rosa G, Galli V, Melillo RM, Santoro M.
Overexpression of the cytokine osteopontin identifies aggressive laryngeal squamous cell carcinomas and enhances carcinoma cell proliferation and invasiveness.

Milano A; Montesano Gesualdi N; Teperino R; Esposito F; Cocozza S; Ungaro P.
Oxidative DNA damage and activation of c-Jun N-terminal kinase pathway in fibroblasts from patients with hereditary spastic paraplegia.

Dentice M, Luongo C, Elefante A, Ambrosio R, Salzano S, Zannini M, Nitsch R, Di Lauro R, Rossi G, Fenzi G, Salvatore D.
Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells.

Sarnataro D, Grimaldi C, Pisanti S, Gazzerro P, Laezza C, Zurzolo C, Bifulco M.
Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells.

Svegliati S; Cancello R; Sambo P; Luchetti M; Paroncini P; Orlandini G; Discepoli G; Paterno R; Santillo M; Cuozzo C; Cassano S; Avvedimento EV; Gabrielli A.
Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts.

Fusco A, Viglietto G, Santoro M.
Point mutation in GRIM-19: a new genetic lesion in Hurthle cell thyroid carcinomas.

Oriente F; Andreozzi F; Romano C; Perruolo G; Perfetti A; Fiory F; Miele C; Beguinot F; Formisano P.
Protein kinase C-alpha regulates insulin action and degradation by interacting with insulin receptor substrate-1 and 14-3-3epsilon.

De Falco V, Guarino V, Malorni L, Cirafici AM, Troglio F, Erreni M, Pelicci G, Santoro M, Melillo RM.
RAI(ShcC/N-Shc)-dependent recruitment of GAB 1 to RET oncoproteins potentiates PI 3-K signalling in thyroid tumors.

Formisano P; Perruolo G; Libertini S; Santopietro S; Troncone G; Raciti GA; Oriente F; Portella G; Miele C; Beguinot F.
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.

Carlomagno F, Santoro M.
Receptor tyrosine kinases as targets for anticancer therapeutics.

Motti ML, Califano D, Baldassarre G, Celetti A, Merolla F, Forzati F, Napolitano M, Tavernise B, Fusco A, Viglietto G.
Reduced E-cadherin expression contributes to the loss of p27kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.

Pera IL, Iuliano R, Florio T, Susini C, Trapasso F, Santoro M, Chiariotti L, Schettini G, Viglietto G, Fusco A.
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.

Melillo RM; Castellone MD; Guarino V; De Falco V; Cirafici AM; Salvatore G; Caiazzo F; Basolo F; Giannini R; Kruhoffer M; Orntoft T; Fusco A; Santoro M.
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells.

D’Andrea B, Di Palma T, Mascia A, Motti ML, Viglietto G, Nitsch L, Zannini M.
The transcriptional repressor DREAM is involved in thyroid gene expression.

Fedele M; Pentimalli F; Baldassarre G; Battista S; Klein-Szanto AJ; Kenyon L; Visone R; De Martino I; Ciarmiello A; Arra C; Viglietto G; Croce CM; Fusco A.
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.

Garcia-Barcelo M, Ganster RW, Lui VC, Leon TY, So MT, Lau AM, Fu M, Sham MH, Knight J, Zannini MS, Sham PC, Tam PK.
TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung’s disease.

Fiory F; Alberobello A. T.; Miele C.; Oriente F.; Esposito I.; Corbo V.; Ruvo M.; Tizzano B.; Rasmussen T.E.; Gammeltoft S.; Formisano P.; and Beguinot F.
Tyrosine phosphorylation of Phosphoinositide-dependent kinase-1 by the insulin receptor is necessary for insulin metabolic signaling.

P Pallante1, MT Berlingieri1, G Troncone2, M Kruhoffer3, TF Orntoft3, G Viglietto1, A Caleo2, I Migliaccio2, M Decaussin-Petrucci4, M Santoro1, L Palombini2 and A Fusco*,1,5
UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas.