Publications

Year 2015

  Monaco S.; Rusciano M.R.; Maione A.S.; Soprano M.; Gomathinayagam R.; Todd L.R.; Campiglia P.; Salzano S.; Pastore L.; Leggiero E.; Wilkerson D.C.; Rocco M.; Selleri C.; Iaccarino G.; Sankar U.; Illario M. A novel crosstalk between calcium/calmodulin kinases II and IV regulates cell proliferation in myeloid leukemia cells Catuogno S.; Esposito C.L.; De Franciscis V. A Trojan horse for human immunodeficiency virus Pisanti S1, Picardi P, Pallottini V, Martini C, Petrosino S, Proto MC, Vitale M, Laezza C, Gazzerro P, Di Marzo V, Bifulco M. Anandamide Drives Cell Cycle Progression through CB1 Receptors in a Rat Model of Synchronized Liver Regeneration. Fedele M.; Gualillo O.; Vecchione A. Animal models of human pathology 2014 Claudio Procaccini a, VeronicaDeRosa a,b, ValentinaPucino c, LuigiFormisano d, Giuseppe Matarese Animal models of Multiple Sclerosis Procaccini C1, De Rosa V2, Pucino V3, Formisano L4, Matarese G5. Animal models of Multiple Sclerosis. Refolo MG1, D'Alessandro R, Malerba N, Laezza C, Bifulco M, Messa C, Caruso MG, Notarnicola M, Tutino V. Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines. Fiore D1, Proto MC1, Pisanti S1, Picardi P1, Pagano Zottola AC1, Butini S2, Gemma S2, Casagni A2, Laezza C3, Vitale M4, Ligresti A5, Di Marzo V5, Zisterer DM6, Nathwani S6, Williams DC6, Campiani G2, Gazzerro P1, Bifulco M4. Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. Bongiovanni A., Colotti G., Liguori G.L., Di Carlo M., Digilio F.A., Lacerra G., Mascia A., Cirafici A.M., Barra A., Lanati A. and Kisslinger A. Applying Quality principles and Project Management methodologies in biomedical research: a public research network's case study. Camorani S1, Crescenzi E1, Colecchia D2, Carpentieri A3, Amoresano A3, Fedele M1, Chiariello M2, Cerchia L1. Aptamer targeting EGFRvIII mutant hampers its constitutive autophosphorylation and affects migration, invasion and proliferation of glioblastoma cells. Esposito CL1, Catuogno S1, de Franciscis V2. Aptamer-MiRNA Conjugates for Cancer Cell-Targeted Delivery. Condorelli, Gerolama; Giangrande, Paloma H; de Franciscis, Vittorio Arresting the colonial destiny of metastatic seeds with DNA aptamers. Valentino R1, D'Esposito V, Ariemma F, Cimmino I, Beguinot F, Formisano P. Bisphenol A environmental exposure and the detrimental effects on human metabolic health: is it necessary to revise the risk assessment in vulnerable population? Savastano, Silvia; Tarantino, Giovanni; D'Esposito, Vittoria; Passaretti, Federica; Cabaro, Serena; Liotti, Antonietta; Liguoro, Domenico; Perruolo, Giuseppe; Ariemma, Fabiana; Finelli, Carmine; Beguinot, Francesco; Formisano, Pietro; Valentino, Rossella Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population. Ciaglia E1,2, Torelli G3,4, Pisanti S1,2, Picardi P1,2, D'Alessandro A2, Laezza C5,6, Malfitano AM1,2, Fiore D2, Pagano Zottola AC2, Proto MC2, Catapano G3, Gazzerro P2, Bifulco M1,2. Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cells. Leone V1, Langella C1, Esposito F1, Arra C2, Palma G2, Rea D2, Paciello O3, Merolla F1, De Biase D3, Papparella S3, Celetti A1, Fusco A1,4. Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity. Somma D, Mastrovito P, Grieco M, Lavorgna A, Pignalosa A, Formisano L, Salzano AM, Scaloni A, Pacifico F, Siebenlist U, Leonardi A. CIKS/DDX3X Interaction Controls the Stability of the Zc3h12a mRNA Induced by IL-17. Mirra P.; Raciti G.A.; Nigro C.; Fiory F.; D'Esposito V.; Formisano P.; Beguinot F.; Miele C. Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes Pierantoni G.M.; Conte A.; Rinaldo C.; Tornincasa M.; Gerlini R.; Federico A.; Valente D.; Medico E.; Fusco A. Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes Gian Luigi Russo, Viviana Vastolo, Marco Ciccarelli, Luigi Albano, Paolo Emidio Macchia & Paola Ungaro Dietary Polyphenols and Chromatin Remodelling Russo GL1, Vastolo V2, Ciccarelli M2, Albano L2, Macchia PE3, Ungaro P4. Dietary Polyphenols and Chromatin Remodelling. Carchia, E.; Porreca, I.; Almeida, P. J.; D'Angelo, F.; Cuomo, D.; Ceccarelli, M.; De Felice, M.; Mallardo, M.; Ambrosino, C. Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity Mikko O. Laukkanen1*, Francesca Cammarota1, Tiziana Esposito1, Marco Salvatore2, and Maria Domenica Castellone3 Extracellular Superoxide Dismutase Regulates the Expression of Small GTPase Regulatory Proteins GEFs, GAPs, and GDI F Morra, C Luise, F Merolla, I Poser, R Visconti, H Inuzuka, G Ilardi, G Guggino, R Monaco, D Colecchia, G Monaco, A Cerrato, M Chiariello, Krista Denning, Pier Paolo Claudio, S Staibano and A Celetti FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC. Frett, Brendan; Carlomagno, Francesca; Moccia, Maria Luisa; Brescia, Annalisa; Federico, Giorgia; De Falco, Valentina; Admire, Brittany; Chen, Zhongzhu; Qi, Wenqing; Santoro, Massimo; Li, Hong-yu Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology Cirillo P.; Pellegrino G.; Conte S.; Maresca F.; Pacifico F.; Leonardi A.; Trimarco B. Fructose induces prothrombotic phenotype in human endothelial cells: A new role for "added sugar" in cardio-metabolic risk Laukkanen MO, Castellone MD1. Gastrin-Releasing Peptide Receptor Targeting in Cancer Treatment: Emerging Signaling Networks and Therapeutic Applications. De Rosa V1,2, Galgani M1, Porcellini A3, Colamatteo A2,4, Santopaolo M5, Zuchegna C3, Romano A3, De Simone S1, Procaccini C1, La Rocca C1, Carrieri PB6, Maniscalco GT7, Salvetti M8, Buscarinu MC8, Franzese A9, Mozzillo E9, La Cava A10, Matarese G4,11. Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants. Pallante, Pierlorenzo; Sepe, Romina; Puca, Francesca; Fusco, Alfredo High mobility group a proteins as tumor markers. Laukkanen MO, Castellone MD1. Hijacking the Hedgehog Pathway in Cancer Therapy. Valente D.; Bossi G.; Moncada A.; Tornincasa M.; Indelicato S.; Piscuoglio S.; Karamitopoulou E.D.; Bartolazzi A.; Pierantoni G.M.; Fusco A.; Soddu S.; Rinaldo C. HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Sepe R.; Piscuoglio S.; Quintavalle C.; Perrina V.; Quagliata L.; Formisano U.; Terracciano L.M.; Fusco A.; Pallante P. HMGA1 overexpression is associated with a particular subset of human breast carcinomas Mirra V.; Caffarelli C.; Maglione M.; Valentino R.; Perruolo G.; Mazzarella C.; Di Micco L.L.; Montella S.; Santamaria F. Hypovitaminosis D: A novel finding in primary ciliary dyskinesia Omodei D.; Pucino V.; Labruna G.; Procaccini C.; Galgani M.; Perna F.; Pirozzi D.; De Caprio C.; Marone G.; Fontana L.; Contaldo F.; Pasanisi F.; Matarese G.; Sacchetti L. Immune-metabolic profiling of anorexic patients reveals an anti-oxidant and anti-inflammatory phenotype Malapelle, Umberto; Vigliar, Elena; Sgariglia, Roberta; Bellevicine, Claudio; Colarossi, Lorenzo; Vitale, Domenico; Pallante, Pierlorenzo; Troncone, Giancarlo Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients Malapelle U1, Vigliar E1, Sgariglia R1, Bellevicine C1, Colarossi L2, Vitale D3, Pallante P4, Troncone G1. Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients. Malapelle U1, Sgariglia R1, De Stefano A2, Bellevicine C1, Vigliar E1, de Biase D3, Sepe R4, Pallante P4, Carlomagno C2, Tallini G3, Troncone G1. KRAS Mutant Allele-Specific Imbalance (MASI) assessment in routine samples of patients with metastatic colorectal cancer. Procaccini C1, Pucino V2, Mantzoros CS3, Matarese G4. Leptin in autoimmune diseases. Carrieri P.B.; Carbone F.; Perna F.; Bruzzese D.; La Rocca C.; Galgani M.; Montella S.; Petracca M.; Florio C.; Maniscalco G.T.; Spitaleri D.L.A.; Iuliano G.; Tedeschi G.; Corte M.D.; Bonavita S.; Matarese G. Longitudinal assessment of immuno-metabolic parameters in multiple sclerosis patients during treatment with glatiramer acetate Visciano C1, Liotti F1, Prevete N2, Cali' G1, Franco R3, Collina F3, de Paulis A2, Marone G2, Santoro M1, Melillo RM1. Mast cells induce epithelial-to-mesenchymal transition and stem cell features in human thyroid cancer cells through an IL-8-Akt-Slug pathway. Mauro C1, De Rosa V2, Marelli-Berg F1, Solito E1. Metabolic syndrome and the immunological affair with the blood-brain barrier. Colamaio M1, Puca F, Ragozzino E, Gemei M, Decaussin-Petrucci M, Aiello C, Bastos AU, Federico A, Chiappetta G, Del Vecchio L, Torregrossa L, Battista S, Fusco A. miR-142-3p Down-Regulation Contributes to Thyroid Follicular Tumorigenesis by Targeting ASH1L and MLL1. Postiglione, Ilaria; Chiaviello, Angela; Barra, Federica; Roscetto, Emanuela; Soriano, Amata A.; Catania, Maria Rosaria; Palumbo, Giuseppe; Pierantoni, Giovanna Maria Mitochondrial Malfunctioning, Proteasome Arrest and Apoptosis in Cancer Cells by Focused Intracellular Generation of Oxygen Radicals Lucci, Valeria; Di Palma, Tina; Zannini, Mariastella Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells. Manera C.; Malfitano A.M.; Parkkari T.; Lucchesi V.; Carpi S.; Fogli S.; Bertini S.; Laezza C.; Ligresti A.; Saccomanni G.; Savinainen J.R.; Ciaglia E.; Pisanti S.; Gazzerro P.; Di Marzo V.; Nieri P.; Macchia M.; Bifulco M. New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity Costa V1, Esposito R1, Ziviello C1, Sepe R2, Bim LV2, Cacciola NA2, Decaussin-Petrucci M3, Pallante P2, Fusco A2,4, Ciccodicola A1,5. New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma. De Rosa V1, Galgani M2, Santopaolo M3, Colamatteo A4, Laccetti R5, Matarese G6. Nutritional control of immunity: Balancing the metabolic requirements with an appropriate immune function. Camorani, Simona; Cerchia, Laura Oligonucleotide aptamers for glioma targeting: an update. Sabbatini M.; Ruggiero G.; Palatucci A.T.; Rubino V.; Federico S.; Giovazzino A.; Apicella L.; Santopaolo M.; Matarese G.; Galgani M.; Terrazzano G. Oscillatory mTOR inhibition and Treg increase in kidney transplantation Laezza C1, D'Alessandro A2,3, Di Croce L4, Picardi P2,3, Ciaglia E2,3, Pisanti S2,3, Malfitano AM2,3, Comegna M5,6, Faraonio R5,6, Gazzerro P2,3, Bifulco M2,3. p53 regulates the mevalonate pathway in human glioblastoma multiforme. Carrizzo A1, Lenzi P2, Procaccini C3, Damato A1, Biagioni F1, Mariateresa A1, Amodio G4, Remondelli P5, Del Giudice C6, Izzo R6, Malovini A7, Formisano L8, Gigantino V9, Madonna M1, Puca AA10, Trimarco B6, Matarese G10, Fornai F11, Vecchione C12. Pentraxin 3 Induces Vascular Endothelial Dysfunction Through a P-selectin/MMP-1 Pathway. Barra, Federica; Roscetto, Emanuela; Soriano, Amata A.; Vollaro, Adriana; Postiglione, Ilaria; Pierantoni, Giovanna Maria; Palumbo, Giuseppe; Catania, Maria Rosaria Photodynamic and Antibiotic Therapy in Combination to Fight Biofilms and Resistant Surface Bacterial Infections D'Esposito V1, Passaretti F1, Perruolo G2, Ambrosio MR1, Valentino R2, Oriente F1, Raciti GA2, Nigro C2, Miele C2, Sammartino G3, Beguinot F1,2, Formisano P1,2. Platelet-Rich Plasma Increases Growth and Motility of Adipose Tissue-Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function. Cocco S.; Secondo A.; Del Viscovo A.; Procaccini C.; Formisano L.; Franco C.; Esposito A.; Scorziello A.; Matarese G.; Di Renzo G.; Canzoniero L.M.T. Polychlorinated biphenyls induce mitochondrial dysfunction in SH-SY5Y neuroblastoma cells Pallante, Pierlorenzo; Forzati, Floriana; Federico, Antonella; Arra, Claudio; Fusco, Alfredo Polycomb protein family member CBX7 plays a critical role in cancer progression Criscuolo C.; Procaccini C.; Meschini M.C.; Cianflone A.; Carbone R.; Doccini S.; Devos D.; Nesti C.; Vuillaume I.; Pellegrino M.; Filla A.; de Michele G.; Matarese G.; Santorelli F.M. Powerhouse failure and oxidative damage in autosomal recessive spastic ataxia of Charlevoix-Saguenay Conte A, Pierantoni GM1. Regulation of HIPK Proteins by MicroRNAs. Galgani M1, Insabato L2, Calì G1, Della Gatta AN3, Mirra P4, Papaccio F1, Santopaolo M5, Alviggi C3, Mollo A3, Strina I3, Matarese G6, Beguinot F4, De Placido G3, Ulianich L7. Regulatory T cells, inflammation, and endoplasmic reticulum stress in women with defective endometrial receptivity. Cacciola N.A.; Sepe R.; Forzati F.; Federico A.; Pellecchia S.; Malapelle U.; de Stefano A.; Rocco D.; Fusco A.; Pallante P. Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment Catuogno S1, Rienzo A1, Di Vito A1, Esposito CL1, de Franciscis V2. Selective delivery of therapeutic single strand antimiRs by aptamer-based conjugates. Iervolino A1, Trepiccione F2, Petrillo F3, Spagnuolo M4, Scarfò M1, Frezzetti D1, De Vita G5, De Felice M6, Capasso G2. Selective Dicer Suppression in the Kidney Alters gsk3?/?-Catenin Pathways Promoting a Glomerulocystic Disease. Laukkanen M.O.; Gutkind J.S.; Castellone M.D. Sonic Hedgehog in SCLC Galgani M.; Rosa V.D.; Matarese G. T cell metabolism and susceptibility to autoimmune diseases Costa V1, Esposito R, Pallante P, Ciccodicola A, Fusco A. The "next-generation" knowledge of papillary thyroid carcinoma. Norata G.D.; Caligiuri G.; Chavakis T.; Matarese G.; Netea M.G.; Nicoletti A.; O'Neill L.A.J.; Marelli-Berg F.M. The Cellular and Molecular Basis of Translational Immunometabolism Leone V.; Ferraro A.; Schepis F.; Federico A.; Sepe R.; Arra C.; Langella C.; Palma G.; De Lorenzo C.; Troncone G.; Masciullo V.; Scambia G.; Fusco A.; Pallante P. The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias R Visconti, R Della Monica, L Palazzo, F D'Alessio, M Raia, S Improta, MR Villa, L Del Vecchio, D Grieco The Fcp1-Wee1-Cdk1 axis affects spindle assembly checkpoint robustness and sensitivity to antimicrotubule cancer drugs Lapice E.; Monticelli A.; Cocozza S.; Pinelli M.; Cocozza S.; Bruzzese D.; Riccardi G.; Vaccaro O. The PPAR?2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes Pappalardo A1, Porreca I2, Caputi L3, De Felice E3, Schulte-Merker S4, Zannini M5, Sordino P6. Thyroid development in zebrafish lacking Taz. Oh-hashi, Kentaro; Sone, Azumi; Hikiji, Takahiro; Hirata, Yoko; Vitiello, Michela; Fedele, Monica; Ishigaki, Shinsuke; Sobue, Gen; Kiuchi, Kazutoshi Transcriptional and post-transcriptional regulation of transmembrane protein 132A Cacciola NA1, Calabrese C, Malapelle U, Pellino G, De Stefano A, Sepe R, Sgariglia R, Quintavalle C, Federico A, Bianco A, Uchimura Bastos A, Milone M, Bellevicine C, Milone F, Carlomagno C, Selvaggi F, Troncone G, Fusco A, Pallante P. UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients. Raciti G.A.; Longo M.; Parrillo L.; Ciccarelli M.; Mirra P.; Ungaro P.; Formisano P.; Miele C.; Beguinot F. Understanding type 2 diabetes: from genetics to epigenetics