Contributi in rivista

Anno 2012

Rendina D, Esposito T, Mossetti G, De Filippo G, Gianfrancesco F, Perfetti A, Magliocca S, Formisano P, Prié D, Strazzullo P.
A functional allelic variant of the FGF23 gene is associated with renal phosphate leak in calcium nephrolithiasis.

Faraonio R, Salerno P, Passaro F, Sedia C, Iaccio A, Bellelli R, Nappi TC, Comegna M, Romano S, Salvatore G, Santoro M, Cimino F.
A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts.

Tamburrino A, Molinolo AA, Salerno P, Chernock RD, Raffeld M, Xi L, Gutkind JS, Moley JF, Wells SA Jr, Santoro M.
Activation of the mTOR pathway in primary medullary thyroid carcinoma and lymph node metastases.

D’Esposito V, Passaretti F, Hammarstedt A, Liguoro D, Terracciano D, Molea G, Canta L, Miele C, Smith U, Beguinot F, Formisano P.
Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro.

Santulli G, Lombardi A, Sorriento D, Anastasio A, Del Giudice C, Formisano P, Béguinot F, Trimarco B, Miele C, Iaccarino G.
Age-related impairment in insulin release: the essential role of ?(2)-adrenergic receptor.

D’Angelo D, Palmieri D, Mussnich P, Roche M, Wierinckx A, Raverot G, Fedele M, Croce CM, Trouillas J, Fusco A.
Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1.

de Cristofaro T, Di Palma T, Fichera I, Lucci V, Parrillo L, De Felice M, Zannini M.
An Essential Role for Pax8 in the Transcriptional Regulation of Cadherin-16 in Thyroid Cells.

Laezza C, D’Alessandro A, Paladino S, Maria Malfitano A, Chiara Proto M, Gazzerro P, Pisanti S, Santoro A, Ciaglia E, Bifulco M
Anandamide inhibits the Wnt/?-catenin signalling pathway in human breast cancer MDA MB 231 cells.

Fedele M, Gualillo O, Vecchione A.
Animal models of human pathology 2012.

Matarese G, Procaccini C, De Rosa V.
At the crossroad of T cells, adipose tissue, and diabetes.

Giordano, Arturo; Romano, Simona; Nappo, Giovanna; Messina, Stefano; Polimeno, Michele; Corcione, Nicola; Calì, Gaetano; Ferraro, Paolo; Monaco, Mario; Zambrano, Nicola; Romano, Maria Fiammetta
Atorvastatin Sensitises Vascular Smooth Muscle Cells, but not Endothelial Cells, to TNF-alpha-induced Cell Death

Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G.
CaMK4 Gene Deletion Induces Hypertension.

Forzati F, Federico A, Pallante P, Abbate A, Esposito F, Malapelle U, Sepe R, Palma G, Troncone G, Scarfò M, Arra C, Fedele M, Fusco A.
CBX7 is a tumor suppressor in mice and humans.

De Falco V, Tamburrino A, Ventre S, Castellone MD, Malek M, Manié SN, Santoro M.
CD44 proteolysis increases CREB phosphorylation and sustains proliferation of thyroid cancer cells.

Ward Y, Lake R, Martin PL, Killian K, Salerno P, Wang T, Meltzer P, Merino M, Cheng SY, Santoro M, Garcia-Rostan G, Kelly K.
CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model.

Calì G, Gentile F, Mogavero S, Pallante P, Nitsch R, Ciancia G, Ferraro A, Fusco A, Nitsch L.
CDH16/Ksp-Cadherin Is Expressed in the Developing Thyroid Gland and Is Strongly Down-Regulated in Thyroid Carcinomas.

Treglia AS, Turco S, Ulianich L, Ausiello P, Lofrumento DD, Nicolardi G, Miele C, Garbi C, Beguinot F, Di Jeso B.
Cell fate following ER stress: just a matter of “quo ante” recovery or death?

Liu Y, Yu Y, Matarese G, La Cava A.
Cutting edge: fasting-induced hypoleptinemia expands functional regulatory T cells in systemic lupus erythematosus.

Torregrossa L, Giannini R, Borrelli N, Sensi E, Melillo RM, Leocata P, Materazzi G, Miccoli P, Santoro M, Basolo F.
CXCR4 expression correlates with the degree of tumor infiltration and BRAF status in papillary thyroid carcinomas.

Esposito F, Tornincasa M, Pallante P, Federico A, Borbone E, Pierantoni GM, Fusco A.
Down-regulation of the miR-25 and miR-30d contributes to the development of anaplastic thyroid carcinoma targeting the polycomb protein EZH2.

Palmieri D, D’Angelo D, Valentino T, De Martino I, Ferraro A, Wierinckx A, Fedele M, Trouillas J, Fusco A. Source
Downregulation of HMGA-targeting microRNAs has a critical role in human pituitary tumorigenesis.

Quintavalle C, Donnarumma E, Iaboni M, Roscigno G, Garofalo M, Romano G, Fiore D, De Marinis P, Croce CM, Condorelli G.
Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells.

Bifulco G, Miele C, Di Jeso B, Beguinot F, Nappi C, Di Carlo C, Capuozzo S, Terrazzano G, Insabato L, Ulianich L.
Endoplasmic reticulum stress is activated in endometrial adenocarcinoma.

Visconti R; Palazzo L; Della Monica R; Grieco D
Fcp-1 dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit

Visconti R, Palazzo L, Della Monica R, Grieco D.
Fcp1-dependent dephosphorylation is required for M-phase-promoting factor inactivation at mitosis exit.

Bellelli R, Castellone MD, Garcia-Rostan G, Ugolini C, Nucera C, Sadow PM, Nappi TC, Salerno P, Cantisani MC, Basolo F, Gago TA, Salvatore G, Santoro M.
FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma.

Esposito F, Tornincasa M, Federico A, Chiappetta G, Pierantoni GM, Fusco A.
High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria.

Bloch M, Prock A, Paonessa F, Benz V, Bähr IN, Herbst L, Witt H, Kappert K, Spranger J, Stawowy P, Unger T, Fusco A, Sedding D, Brunetti A, Foryst-Ludwig A, Kintscher U.
High-mobility group A1 protein: a new coregulator of peroxisome proliferator-activated receptor-?-mediated transrepression in the vasculature.

Rinaldo C, Moncada A, Gradi A, Ciuffini L, D’Eliseo D, Siepi F, Prodosmo A, Giorgi A, Pierantoni GM, Trapasso F, Guarguaglini G, Bartolazzi A, Cundari E, Schininà ME, Fusco A, Soddu S.
HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody.

Piscuoglio S, Zlobec I, Pallante P, Sepe R, Esposito F, Zimmermann A, Diamantis I, Terracciano L, Fusco A, Karamitopoulou E.
HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma.

Luise C, Merolla F, Leone V, Paladino S, Sarnataro D, Fusco A, Celetti A.
Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcriptional activity.

Carbone F, La Rocca C, Matarese G.
Immunological functions of leptin and adiponectin.

Quintavalle C, Fiore D, De Micco F, Visconti G, Focaccio A, Golia B, Ricciardelli B, Donnarumma E, Bianco A, Zabatta MA, Troncone G, Colombo A, Briguori C, Condorelli G.
Impact of a high loading dose of atorvastatin on contrast-induced acute kidney injury.

Matarese G, La Cava A, Horvath TL.
In vivo veritas, in vitro artificia.

Lombardi A, Ulianich L, Treglia AS, Nigro C, Parrillo L, Lofrumento DD, Nicolardi G, Garbi C, Beguinot F, Miele C, Di Jeso B. Source
Increased hexosamine biosynthetic pathway flux dedifferentiates INS-1E cells and murine islets by an extracellular signal-regulated kinase (ERK)1/2-mediated signal transmission pathway.

Liotti F, Visciano C, Melillo RM.
Inflammation in thyroid oncogenesis.

Botta G, Passaro C, Libertini S, Abagnale A, Barbato S, Maione AS, Hallden G, Beguinot F, Formisano P, Portella G.
Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo.

Proto MC, Gazzerro P, Di Croce L, Santoro A, Malfitano AM, Pisanti S, Laezza C, Bifulco M.
Interaction of endocannabinoid system and steroid hormones in the control of colon cancer cell growth.

Procaccini C, Galgani M, De Rosa V, Matarese G.
Intracellular metabolic pathways control immune tolerance.

Paduano F, Ortuso F, Campiglia P, Raso C, Iaccino E, Gaspari M, Gaudio E, Mangone G, Carotenuto A, Bilotta A, Narciso D, Palmieri C, Agosti V, Artese A, Gomez-Monterrey I, Sala M, Cuda G, Iuliano R, Perrotti N, Scala G, Viglietto G, Alcaro S, Croce CM, Novellino E, Fusco A, Trapasso F.
Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity.

Procaccini C, De Rosa V, Galgani M, Carbone F, Cassano S, Greco D, Qian K, Auvinen P, Calì G, Stallone G, Formisano L, La Cava A, Matarese G.
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses.

Claudio Procaccini, Veronica De Rosa, Mario Galgani, Fortunata Carbone, Silvana Cassano, Dario Greco,Kui Qian, Petri Auvinen, Gaetano Calì, Giovanni Stallone, Luigi Formisano, Antonio La Cava, and Giuseppe Matarese
Leptin-induced mTOR Activation Defines a Specific Molecular and Transcriptional Signature Controlling CD4+ Effector TCell Responses

Colamaio, Marianna; Calì, Gaetano; Sarnataro, Daniela; Borbone, Eleonora; Pallante, Pierlorenzo; Decaussin-Petrucci, Myriam; Nitsch, Lucio; Croce, Carlo Maria; Battista, Sabrina; Fusco, Alfredo
Let-7a Down-Regulation Plays a Role in Thyroid Neoplasias of Follicular Histotype Affecting Cell Adhesion and Migration through Its Ability to Target the FXYD5 (Dysadherin) Gene

Colamaio M, Calì G, Sarnataro D, Borbone E, Pallante P, Decaussin-Petrucci M, Nitsch L, Croce CM, Battista S, Fusco A.
Let-7a Down-Regulation Plays a Role in Thyroid Neoplasias of Follicular Histotype Affecting Cell Adhesion and Migration through Its Ability to Target the FXYD5 (Dysadherin) Gene.

Merolla F, Luise C, Muller MT, Pacelli R, Fusco A, Celetti A.
Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage.

Beguinot F, Nigro C.
Measurement of glucose homeostasis in vivo: glucose and insulin tolerance tests.

M Acunzo1, R Visone1, G Romano2, A Veronese1, F Lovat1, D Palmieri1,3, A Bottoni1, M Garofalo1, P Gasparini1, G Condorelli3, M Chiariello4 and CM Croce1
miR-130a targets MET and induces TRAIL-sensitivity in NSCLC by downregulating miR-221 and 222

Catuogno S, Cerchia L, Romano G, Pognonec P, Condorelli G, de Franciscis V.
miR-34c may protect lung cancer cells from paclitaxel-induced apoptosis.

Romano G, Acunzo M, Garofalo M, Di Leva G, Cascione L, Zanca C, Bolon B, Condorelli G, Croce CM.
MiR-494 is regulated by ERK1/2 and modulates TRAIL-induced apoptosis in non-small-cell lung cancer through BIM down-regulation.

Miele C, Beguinot F.
New expectations from the well-known medicinal properties of Arctium lappa.

Heiliger KJ, Hess J, Vitagliano D, Salerno P, Braselmann H, Salvatore G, Ugolini C, Summerer I, Bogdanova T, Unger K, Thomas G, Santoro M, Zitzelsberger H.
Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.

Catuogno S, Esposito CL, Quintavalle C, Condorelli G, de Franciscis V, Cerchia L.
Nucleic acids in human glioma treatment: innovative approaches and recent results.

Matarese G, De Rosa V.
Ob-stopping obesity, metabolic and immune-mediated disorders.

Sassolas G, Hafdi-Nejjari Z, Ferraro A, Decaussin-Petrucci M, Rousset B, Borson-Chazot F, Borbone E, Berger N, Fusco A.
Oncogenic alterations in papillary thyroid cancers of young patients.

Mascolo M, Ilardi G, Romano MF, Celetti A, Siano M, Romano S, Luise C, Merolla F, Rocco A, Vecchione ML, De Rosa G, Staibano S.
Overexpression of chromatin assembly factor-1 p60, poly(ADP-ribose) polymerase 1 and nestin predicts metastasizing behaviour of oral cancer.

Buonomo R, Giacco F, Vasaturo A, Caserta S, Guido S, Pagliara V, Garbi C, Mansueto G, Cassese A, Perruolo G, Oriente F, Miele C, Beguinot F, Formisano P.
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms.

Iovino S, Oriente F, Botta G, Cabaro S, Iovane V, Paciello O, Viggiano D, Perruolo G, Formisano P, Beguinot F.
PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation.

Ungaro P, Mirra P, Oriente F, Nigro C, Ciccarelli M, Vastolo V, Longo M, Perruolo G, Spinelli R, Formisano P, Miele C, Beguinot F.
Peroxisome proliferator-activated receptor-? activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1.

Gazzerro P, Proto MC, Gangemi G, Malfitano AM, Ciaglia E, Pisanti S, Santoro A, Laezza C, Bifulco M.
Pharmacological Actions of Statins: A Critical Appraisal in the Management of Cancer.

Palmieri D, Valentino T, De Martino I, Esposito F, Cappabianca P, Wierinckx A, Vitiello M, Lombardi G, Colao A, Trouillas J, Pierantoni GM, Fusco A, Fedele M.
PIT1 upregulation by HMGA proteins has a role in pituitary tumorigenesis.

Pero R, Palmieri D, Angrisano T, Valentino T, Federico A, Franco R, Lembo F, Klein-Szanto AJ, Del Vecchio L, Montanaro D, Keller S, Arra C, Papadopoulou V, Wagner SD, Croce CM, Fusco A, Chiariotti L, Fedele M.
POZ-, AT-hook-, and zinc finger-containing protein (PATZ) interacts with human oncogene B cell lymphoma 6 (BCL6) and is required for its negative autoregulation.

Manera C, Saccomanni G, Malfitano AM, Bertini S, Castelli F, Laezza C, Ligresti A, Lucchesi V, Tuccinardi T, Rizzolio F, Bifulco M, Di Marzo V, Giordano A, Macchia M, Martinelli A.
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold.

Procaccini C, Matarese G.
Regulatory T cells, mTOR kinase, and metabolic activity.

Crescenzi E, De Palma R, Leonardi A.
Senescence and NF?B: A trojan horse in tumors?

Cerchia L, Esposito CL, Camorani S, Rienzo A, Stasio L, Insabato L, Affuso A, de Franciscis V.
Targeting Axl with an high-affinity inhibitory aptamer.

Cirillo P, Di Palma V, Maresca F, Pacifico F, Ziviello F, Bevilacqua M, Trimarco B, Leonardi A, Chiariello M.
The adipokine visfatin induces tissue factor expression in human coronary artery endothelial cells: another piece in the adipokines puzzle.

Malfitano AM, Laezza C, Galgani M, Matarese G, D’Alessandro A, Gazzerro P, Bifulco M.
The CB1 receptor antagonist rimonabant controls cell viability and ascitic tumour growth in mice.

Esposito F, Boscia F, Gigantino V, Tornincasa M, Fusco A, Franco R, Chieffi P.
The high-mobility group A1-estrogen receptor ? nuclear interaction is impaired in human testicular seminomas.

Iiritano S, Chiefari E, Ventura V, Arcidiacono B, Possidente K, Nocera A, Nevolo MT, Fedele M, Greco A, Greco M, Brunetti G, Fusco A, Foti D, Brunetti A.
The HMGA1-IGF-I/IGFBP system: a novel pathway for modulating glucose uptake.

Bruzzone S, Ameri P, Briatore L, Mannino E, Basile G, Andraghetti G, Grozio A, Magnone M, Guida L, Scarfì S, Salis A, Damonte G, Sturla L, Nencioni A, Fenoglio D, Fiory F, Miele C, Beguinot F, Ruvolo V, Bormioli M, Colombo G, Maggi D, Murialdo G, Cordera
The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts.

Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, Ryffel GU, Lam EW, Kist R, Wilson MS, Marco-Ferreres R, Brosens JJ, Beccari LL, Bovolenta P, Benayoun BA, Monteiro LJ, Schwenen HD, Grontved L, Wederell E, Mandrup S, Veitia RA, Chakravarthy H, Hoodless PA, Mancarelli MM, Torbett BE, Banham AH, Reddy SP, Cullum RL, Liedtke M, Tschan MP, Vaz M, Rizzino A, Zannini M, Frietze S, Farnham PJ, Eijkelenboom A, Brown PJ, Laperrière D, Leprince D, de Cristofaro T, Prince KL, Putker M, del Peso L, Camenisch G, Wenger RH, Mikula M, Rozendaal M, Mader S, Ostrowski J, Rhodes SJ, Van Rechem C, Boulay G, Olechnowicz SW, Breslin MB, Lan MS, Nanan KK, Wegner M, Hou J, Mullen RD, Colvin SC, Noy PJ, Webb CF, Witek ME, Ferrell S, Daniel JM, Park J, Waldman SA, Peet DJ, Taggart M, Jayaraman PS, Karrich JJ, Blom B, Vesuna F, O’Geen H, Sun Y, Gronostajski RM, Woodcroft MW, Hough MR, Chen E, Europe-Finner GN, Karolczak-Bayatti M, Bailey J, Hankinson O, Raman V, LeBrun DP, Biswal S, Harvey CJ, DeBruyne JP, Hogenesch JB, Hevner RF, Héligon C, Luo XM, Blank MC, Millen KJ, Sharlin DS, Forrest D, Dahlman-Wright K, Zhao C, Mishima Y, Sinha S, Chakrabarti R, Portales-Casamar E, Sladek FM, Bradley PH, Wasserman WW.
The transcription factor encyclopedia.

Leone V, D’Angelo D, Pallante P, Croce CM, Fusco A.
Thyrotropin regulates thyroid cell proliferation by up-regulating miR-23b and miR-29b that target SMAD3.

Forzati F, Federico A, Pallante P, Fedele M, Fusco A.
Tumor suppressor activity of CBX7 in lung carcinogenesis.

Wells SA Jr, Robinson BG, Gagel RF, Dralle H, Fagin JA, Santoro M, Baudin E, Elisei R, Jarzab B, Vasselli JR, Read J, Langmuir P, Ryan AJ, Schlumberger MJ.
Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial.

De Menna M, D’Amato V, Ferraro A, Fusco A, Di Lauro R, Garbi C, De Vita G.
Wnt4 inhibits cell motility induced by oncogenic Ras.

Shiozaki A, Shen-Tu G, Bai X, Iitaka D, De Falco V, Santoro M, Keshavjee S, Liu M.
XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt.